Pylake 1.6.0

Here is an overview of features that were released in Pylake v1.6.0.

New example notebooks

Three new notebooks were added to the documentation, with examples of full analysis workflows: Binding lifetime analysis, hairpin fitting and phase separation.

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Bead-bead coupling correction

When performing active calibration with two beads coupling effects can bias the estimated calibration parameters (force and displacement sensitivity, and the stiffness). In Pylake 1.6.0, we include a model to account for bead-bead coupling between two beads in bulk. See theory and tutorial and the example for more information.

../../_images/correction_factor_whatsnew.png

Force calibration

We have introduced easier access to force calibration parameters and results.

../../_images/focal_listing.png

Extracting the force calibration parameters required to reproduce the Bluelake calibration can now be done with a single command named calibration_params().

Similarly, the active calibration peak as well as the exclusion ranges can now be plotted with a single line of code.

../../_images/focal_plot.png

The force calibration documentation has also been improved. See tutorial and theory for more information.